Product Description: m-PEG11-acid is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG11-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
Applications: Cancer-programmed cell death
Formula: C24H48O13
References: [1]Wilfried Braje et al. Macrocyclic mcl-1 inhibitors and methods of use. WO2019035927A1./[2] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.