m-PEG12-amine, CAS 1977493-48-3

Product Description: m-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG12-amine is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

Applications: Cancer-programmed cell death

Formula: C25H53NO12

References: [1]Vasco AV, et al. A Multicomponent Stapling Approach to Exocyclic Functionalized Helical Peptides: Adding Lipids, Sugars, PEGs, Labels, and Handles to the Lactam Bridge. Bioconjug Chem. 2019 Jan 16;30(1):253-259./[2] Joseph Fox, et al. Methods for inducing bioorthogonal reactivity. WO2017106427A1.

CAS Number: 1977493-48-3

Molecular Weight: 559.69

Compound Purity: 99.74

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-140227-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-140227-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK