Product Description: M3554 is a novel anti-GD2 ADC designed based on humanized ch14.18 anti-GD2 antibody and has anti-tumor activity. The cytotoxicity of M3554 against the GD2-positive neuroblastoma cell line CHP134 was in the subnanomolar IC50 range.
Applications: Cancer-programmed cell death
Formula: N/A
References: [1]Amendt C, et al. Abstract ND08: M3554, a novel anti-GD2 antibody drug conjugate[J]. Cancer Research, 2024, 84(7_Supplement): ND08-ND08.
Molecular Weight: N/A
Research Area: cancer
Solubility: 10 mM in DMSO
Target: CD2