MASP1 Polyclonal Antibody, Rabbit

Abbreviation: MASP1

Target Synonym: MASP1;3MC1;CRARF;CRARF1;MAP1;MASP;MASP3;MAp44;PRSS5;RaRF

Conjugation: Unconjugated

UNIProt ID: P48740

Background: This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human MASP1

Dilution: WB 1:500-1:2000

• SKU: ELSE-AB-92666-60
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-92666-60
• Green Labware: No
• Package Unit: 60 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit