Clone Name: M24
Application Note: WB: 1-5 μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 95
Positive Control: MCF-7
Form: Liquid
Buffer (with preservative): PBS, 50% Glycerol, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008]
Uniprot ID: Q9Y5Y6
Antigen Species: Human
Immunogen: Human native protein
Purification: Purified by protein A
Conjugation: Unconjugated
Full Name: suppression of tumorigenicity 14