Maytansinoid DM4, CAS 799840-96-3

Maytansinoid DM4, CAS 799840-96-3
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MEXHY-100503-0
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MedChemExpress

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Product Description: Maytansinoid DM4 is a thiol-containing maytansine derivative with highly potent cytotoxicity. Maytansinoid DM4 can be used as a cytotoxic moiety of ADC[1][2].

Applications: Cancer-programmed cell death

Formula: C39H56ClN3O10S

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337./[2]Zhao RY, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates. J Med Chem. 2011 May 26;54(10):3606-23.

CAS Number: 799840-96-3

Molecular Weight: 794.39

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin
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SKU MEXHY-100503-0
Manufacturer MedChemExpress
Manufacturer SKU HY-100503-0
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