Product Description: MC-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
Applications: Cancer-programmed cell death
Formula: C23H30N4O6
References: [1]Wayne C Widdison, et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolites in Cancer Cells and Induce High Levels of Bystander Killing. Bioconjug Chem. 2015 Nov 18;26(11):2261-78.
CAS Number: 1949793-44-5
Molecular Weight: 458.51
Compound Purity: 97.32
Research Area: Cancer
Solubility: DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)