Clone Name: GT1306
Application Note: WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 43
Form: Liquid
Buffer (with preservative): PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
Concentration: 1.14 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]
Uniprot ID: Q02750
Antigen Species: Human
Immunogen: A phospho specific peptide corresponding to residues surrounding T292 of human MEK1.
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: mitogen-activated protein kinase kinase 1