Methyl 1-Cbz-azetidine-3-carboxylate, CAS 757239-60-4

Product Description: Methyl 1-Cbz-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Cbz-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1

Applications: Cancer-programmed cell death

Formula: C13H15NO4

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337./[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

CAS Number: 757239-60-4

Molecular Weight: 249.26

Compound Purity: 99.62

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-W019226-25G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W019226-25G
• Green Labware: No
• Package Unit: 25 g
• Quantity Unit: STK