Clone Name: MITF/2987R
Application Note: ICC/IF: 1-2 μg/ml. IHC-P: 1-2 μg/ml. FACS: 1-2 μg/million cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 59
Specificity/Sensitivity: This antibody recognizes a nuclear protein, which is expressed in the majority of primary and metastatic epithelioid malignant melanomas as well as in normal melanocytes, benign nevi and dysplastic nevi.,We do not recommend use of this product for Mouse,Rat.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]
Uniprot ID: O75030
Antigen Species: Human
Immunogen: Recombinant full-length human MiTF protein
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: melanocyte inducing transcription factor
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