Clone Number: alpha sm-1
Immunogen: Synthetic amino terminal decapeptide of alpha smooth muscle isoform of actin.
Concentration: Greater than or equal to 4,5 mg/L
Storage buffer: Tissue culture supernatant with sodium azide
Additional info: Cytoplasmic actins are part of the microfilament system of cytoskeletal proteins. Smooth muscle actin is found in vascular walls, intestinal muscularis mucosae and muscularis propria and in the stroma of various tissues. Enzyme pretreatment may enhance staining in some cases. Human alpha smooth muscle actin. Reactive with smooth muscle cells in blood vessel walls, gut wall, myometrium and arrectores pili of skin. Myoepithelial cells such as those in breast and salivary gland also contain actin.
References: Skalli O et al. The Journal of Cell Biology. 1986; 103:2787-2796/Ramos JG et al. Endocrinology. 2003; 144(7):3206-3215/Suárez-Vilela D and Izquierdo-Garcia FM. Histopathology. 2003; 43(4):398-400
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