Mouse anti-bcl-2 Oncoprotein, clone BCL-2/100/D5 (monoclonal)

Clone Number: bcl-2/100/D5

Immunogen: Synthetic peptide sequence (GAAPAPGIFSSQPGC-COOH).

Concentration: Greater than or equal to 56 mg/L

Storage buffer: Tissue culture supernatant with sodium azide

Additional info: Bcl-2 is a member of a family of proteins that are involved in apoptosis. Bcl-2 is an integral inner mitochondrial membrane protein of 25 kD and has a wide tissue distribution. It is considered to act as an inhibitor of apoptosis. For this reason, bcl-2 expression is inhibited in germinal centers where apoptosis forms part of the B cell production pathway.

References: Von Haefen C et al. Oncogene. 2002; 21(25):4009-4019/Takes RP et al.Journal of Pathology. 2001; 194:298-302/Tweddle DA et al. American Journal of Pathology. 2001; 158(6): 2067-2077

• SKU: SANMONX10214
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MONX10214
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG1
• Host: Mouse
• Conjugate: Unconjugated