Clone Number: F3
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: Blood group Lewis carbohydrate determinants are oligosaccharides on glycolipids and glycoproteins. In healthy individuals the LewisY antigen is a type 2 antigen usually only expressed in low levels of a few cell types such as some epithelial cells. Reportedly these antigens are aberrantly expressed in high levels in many carcinomas. Anti-BG8, LewisY reactivity in immunohistochemistry is seen in carcinomas of the breast, lung, and colon
References: Davidson B, et al. Virchows Arch. 1999; 435:43-9/King JE, et al. Histopathology. 2006; 48:223-32/Marchevsky AM et al. Appl Immunohistochem Mol Morphol. 2007; 15:140-4