Clone Number: 121SLE
Immunogen: mucins isolated from an ovarian cyst of a 0Lea+b- patient
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: 121SLE reacts with CA19-9 (>400 kDa) or sialyl Lea structure, which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lea and/or Leb blood group antigens. 121SLE also binds to some extend to the afuco version of SLe a (LSTa; CA50). In normal tissues, CA19-9 is present in ductal epithelium of the breast, kidney, salivary, gland and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine and pancreas. 121SLE was typed in the ISOBM TD-6 workshop.
References: Rye PD. et al, Tumor Biol 19 (5): 390-420, (1998)./Christopher MG. et al, Cytojournal 8: 7 (2011)/Rouger et al. Blood transfusion and immunohematol. 30(5): 353-720 (1987)
English
Deutsch
