Mouse anti-Caveolin-1, clone 4D6 (monoclonal)

Clone Number: 4D6

Immunogen: Prokaryotic recombinant protein corresponding to the N-terminus domain of the human caveolin-1 molecule

Concentration: n/a

Storage buffer: Tissue culture supernatant with 15mM sodium azide

Additional info: aveolin-1 is a major structural component of caveolae, which are vesicular invaginations present on the plasma membrane of different cell types. It plays a regulatory role in several signaling pathways and is reported to be most abundantly expressed in terminally differentiated mesenchymal cells such as smooth muscle cells, adipocytes and endothelial cells. High levels are also reported in fibroblasts where a fine granular membranous and diffuse cytoplasmic staining pattern is described.

References: Wiechen K et al. American Journal of Pathology. 158 (3): 833–839 (2001). /Scherer PE et al. PNAS. 93: 131–135 (1996)/Lisanti MP et al. Journal of Cellular Biology. 126 (1): 111–126 (1994).

• SKU: SANMONX11056
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MONX11056
• Green Labware: No
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG2a kappa
• Host: Mouse