Clone Number: 109-3C2
Immunogen: stimulated human leucocytes
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: 109-3C2 binds with CD20 which is a 30/33 kDa non-glycosylated transmembrane phosphoprotein with three extensive hydrophobic regions. CD20 is involved in regulation of B-cell activation. It is expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. Plasma cells are negative. CD20 is retained on many B-cell malignancies. CD20 positive cells are also sometimes found in cases of Hodgkin’s disease, myeloma, and thymoma. 109-3C2 has been clustered at IVth and Vth HLDA Workshops.
References: Knapp W. Leukocyte Typing IV, Oxford Univ. Press, (1989)/Schlossman SF et al. Leukocyte Typing V Oxford University Press: 342-352 (1995)
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