Mouse anti-CD44, clone 145-23 (Monoclonal)

Clone Number: 145-23

Immunogen: stimulated human leucocytes

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: 145-23 reacts with CD44, a type 1 transmembrane glycoprotein providing cell-cell and cellmatrix adhesion while linked to the cytoskeleton. It is involved in haematopoiesis, lymphocyte homing and activation, and tumor metastasis. It binds to fibrin, hyaluronate and other matrix proteins. On tumors CD44H is highly expressed, suggesting an important role in progression for this isoform. CD44 also forms the protein backbone of the human erythrocyte Lutheran antigen system. The epitope of 145-23 is resistant to (chemo)trypsin digestion.

References: Nishina S. et al., Graefes Archiv. Clin. Exp. Opthalm. 235: 92-96 (1997)/Horny H.P. et al. Virchows Arch. 429: 91-94 (1996)

• SKU: SANMON9942
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON9942
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Western Blotting, Flow Cytometry
• Isotype: IgG1-k
• Host: Mouse