Mouse anti-CD68 Recombinant Monoclonal Antibody, Purified (KP-1)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Phosphate Buffered Saline (PBS) with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Protein ID: NP_001242.2

Uniprot ID: P34810

Background: CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins.CD68 is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages [taken from NCBI Entrez Gene (Gene ID: 968)].

Immunogen: Lysosomal fraction of human lung macrophages

• SKU: BEYA500-018ACF
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A500-018ACF
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Immunofluorescence, Flow Cytometry, Immunohistochemistry
• Isotype: Whole IgG
• Human Gene ID: 968
• Host: Mouse
• Conjugate: Unconjugated