Mouse anti-CD8a, clone 143-44 (Monoclonal)

Clone Number: 143-44

Immunogen: human PBL

Concentration: 100 ug/ml

Storage buffer: PBS with 0.02% sodium azide

Additional info: 143-44 recognizes a protein of 32 kDa, identified as CD8a. The CD8 molecule consists of α and β-chains, which are disulphide-linked into heterodimers or homodimers. CD8 is expressed on a T-cell subset (cytotoxic/suppressor T-cells), thymocytes and NK-cells. The majority of CD8+ T-cells express CD8 as heterodimer. Some subpopulation of CD8+ T-cells as well as NK-cells may express homodimer. CD8 functions as a co-receptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 α-chain but not β-chain. 124-1D1 was assigned at the IVth International Workshop.

References: Knapp, W. et. al. Leucocyte Typing IV, p1076, Oxford Univ. Press (1989)

• SKU: SANMON9966
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON9966
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Flow Cytometry
• Isotype: IgG1-k
• Host: Mouse