Clone Number: LP34
Immunogen: Detergent-insoluble fraction of psoriatic human epidermis.
Concentration: n/a
Storage buffer: Tissue culture supernatant with sodium azide
Additional info: Cytokeratins 5, 6 and 18 are reported to be expressed in a broad range of human epithelial tissues, from simple glandular epithelia to stratified squamous epithelia. These include epithelial cells that are ectodermal, mesodermal, or endodermal in origin. These cytokeratins have been reported to be expressed in tumor cells of epithelial origin and less commonly of mesothelial origin. Non-epithelial tumors such as lymphomas do not express these cytokeratins. The recognition of cytokeratin 18 on formalin fixed paraffin embedded sections using clone LP34 may be variable.
References: Lyall F et al. The American Journal of Pathology. 2001;159(5):1827-1838/Yokozaki H et al. Japanese Journal of Clinical Oncology. 2000;30(2):101-104/Lyall F et al. The American Journal of Pathology. 1999;154(4):1105-1114
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