Clone Number: DY8/6C5
Immunogen: Synthetic polypeptide consisting of the last 17 amino acids at the carboxy terminus of the human dystrophin sequence.
Concentration: n/a
Storage buffer: Lyophilized
Additional info: Dystrophin is the 427kD protein product of the DMD gene located on the X chromosome at position Xp21. Analyte Specific Reagent. Analytical and performance characteristics are not established. Product is a lyophilized tissue culture supernatant containing sodium azide as a preservative. The user is required to reconstitute the contents of the vial with the correct volume of sterile distilled water as indicated on the vial label. Reacts strongly with the carboxy terminus (between amino acids 3669 and 3685) of human dystrophin. Also crosssreacts strongly with skeletal, cardiac and smooth muscle dystrophin from normal mouse, rat, rabbit, dog, chicken and hamster. No crossreactivity with mdx mouse tissue. Crossreacts very weakly with pig dystrophin.
References: Marafioti T et al. American Journal of Pathology. 162 (3): 861–871 (2003/Hess J et al. Molecular and Cellular Biology. 21 (5): 1531–1539 (2001)/Re D et al. Cancer Research. 61 (5): 2080–2084 (2001)
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