Mouse anti-Fascin, clone 55-k2

Clone Number: 55-k2

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Fascin is a 55-kd actin bundling protein involved in cell migration. Fascin is up-regulated in many human carcinomas and numerous studies have correlated Fascin over-expression with increased metastatic potential. Fascin is highly sensitive for staining Reed-Sternberg cells making it an excellent marker for classic Hodgkin’s lymphoma. It is uniformly negative in lymphoid cells, plasma cells and myeloid cells. MON 3279 is positive in dendritic cells. This marker may be helpful in distinguishing between Hodgkin’s disease and non-Hodgkin’s lymphoma in difficult cases.

References: Chu Pg Ann Diagn Pathol. 1999;3(2):104-33/Pelosi G et al. Lung Cancer. 2003;42(2):203-13/Goncharuk VN et al. J Cutan Pathol. 2002;29(7):430-8

• SKU: SANMON-RTU1103
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON-RTU1103
• Green Labware: No
• Package Unit: 7 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG1
• Host: Mouse