Clone Number: 9C4
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: Galectin-3 is a 30-kD protein, a member of the beta-galactosidase-binding lectin family. Galectin-3 is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Reportedly, Galectin-3 aberrant expression is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid. Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiation of benign and malignant thyroid neoplasms. Galectin-3 may also be useful in the identification of certain liver disorders.
References: Orlandi F, et al. Cancer Res. 1998; 58:3015-20/Bartolazzi A, et al. Lancet. 2001; 357:1644-50/Papotti M, et al. Eur J Endocrinol. 2002; 147: 515-21
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