Mouse anti-Glypican 3, clone 1G12

Clone Number: 1G12

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Glypican-3 (GPC3) is a membrane-bound heparin sulfate proteoglycan known to participate in cell growth and differentiation. GPC3 expression has been observed in the majority of hepatocellular carcinomas (HCC), but is rarely expressed in non-neoplastic hepatic tissue, making it a useful marker for HCC. Additionally, this marker is expressed in many yolk sac tumors.

References: Kandil DH, et al. Adv Anat Pathol. 2009; 16:125-9/Coston WMP, et al. Am J Surg Pathol. 2008; 32:433-44/Capurro M, et al. Gastroenterology. 2003; 125:89-97

• SKU: SANMON-RTU1117
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON-RTU1117
• Green Labware: No
• Package Unit: 7 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG1
• Host: Mouse