Clone Number: 1F11
Immunogen: GST-hRPP20
Concentration: n/a
Storage buffer: lyophilized in a 10 mM ammoniumbicarbonate buffer. Each vial contains 2 mg BSA
Additional info: The nuclei of eukaryotic cells contain several classes of small RNA-protein complexes. SnRNPs (small nuclear ribonucleoproteins) are involved in splicing of pre-mRNAs (the excision of introns) in the nucleoplasm. RPP20 is part of such a complex. SnoRNPs (small nucleolar ribonucleoproteins) are involved in the maturation of pre-ribosomal RNA in the nucleoli. Pre-rRNA processing and modification require both the snoRNA and the protein constituents (such as Rpp20) of these complexes. Generally, snoRNPs contain a number of common proteins, which are shared with other snoRNPs of the same family, next to several particle-specific proteins. On average, snoRNPs contain about 6-10 protein subunits
References: Welting et al. 2003; 2;313-321/Van Eenennaam et al. IUBMB 2000; 40:265-272/Welting et al. 2004; 32:2138-2046
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