Clone Number: 1D9-M12
Immunogen: L1.2 cells transfected with human C5aR2
Concentration: 1 mg/ml
Format: Purified by protein-A affinity chromatography.
Storage buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Additional info: C5aR2, also known as C5L2, is one of two receptors for C5a (anaphylatoxin). It is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages, and seems to have both pro-inflammatory and anti-inflammatory roles, depending on circumstances. Unlike CD88, C5aR2 is not coupled to G-protein, thus the modulatory role is more likely.SpecificityThe antibody LT10 reacts with an extracellular epitope of CD10 (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.Application detailsFlow cytometry: Recommended dilution: 2-6 µg/ml
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