Clone Number: 4H1
Immunogen: CD116-transfected COS cells
Concentration: 1 mg/ml
Format: Purified by protein-A affinity chromatography.
Storage buffer: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Additional info: CD116 (GM-CSF R alpha) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF). CD116 heterodimerizes with CD131, the common beta chain subunit shared with IL-3 and IL5- receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias.SpecificityThe mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.Application detailsFlow cytometry: Recommended dilution: 1-4 μg/ml.
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