Mouse Anti-Human c-MET(Hepatocyte Growth Factor Receptor), clone 3D4

Clone Number: 3D4

Immunogen: Synthetic peptide derived from cytoplasmic domain of human c-Met protein

Concentration: n/a

Storage buffer: PBS with 1% BSA and 0.1% sodium azide

Additional info: MET is a tyrosine kinase receptor for the hepatocyte growth factor. It is linked to functions such as cell proliferation, scattering, morphogenesis, and survival. Ligand binding at the cell surface induces autophosphorylation of MET that provides docking sites for downstream signaling molecules. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3.

References: Finisguerra V et al. Nature 2015/Mahadevan D et al. Oncotarget 2015/Seiwert TY et al. Cancer Res. 2009

• SKU: SANMON1196
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON1196
• Package Unit: 0,5 ml
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunohistochemistry (paraffin), Immunocytochemistry
• Isotype: Ig2a
• Host: Mouse
• Conjugate: Unconjugated