DENND4C Antibody: ATTO 390

Mouse Anti-Human DENND4C Monoclonal IgG1

Target: DENND4C.

Conjugate: ATTO 390.

Product Type: Monoclonal.

Clone Number: 3E8.

Immunogen: Full Length Human Recombinant Dennd4c protein.

Swiss-Prot: Q5VZ89.

Purification: Protein G Purified.

Storage Buffer: PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide.

Concentration: 1mg/ml.

Specificity: Detects ~213 kDa.

Cellular Localization: Cell membrane , Cytoplasm , Cytoplasmic vesicle , Membrane.

Tissue Specificity: Widely expressed.

Scientific Background: Dennd4c is a guanine nucleotide exchange factor (GEF) for Rab10, and required for GLUT4 translocation (1). It is associated with Alkuraya-Kucinskas Syndrome and Koolen-De Vries Syndrome (2) and interacts with the retromer (3).

References: 1. Sano, H. et al. (2011). J Biol Chem. 286(19):16541-5.2. https://www.genecards.org/cgi-bin/carddisp.pl?gene=DENND4C3. McMillan, K. et al. (2016). J Cell Biol. 214(4):4389–401.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSMC-610D-A390
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SMC-610D-A390
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunocytochemistry
• Isotype: IgG1
• Human Gene ID: 55667
• Host: Mouse