Clone: DCS114.1
Background: The p15ink4b tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16ink4a and p19ink4d. p15ink4b is a specific inhibitor of cdk4/cdk6, and is periodically expressed during cell cycle.
Purification Method: Ammonium Sulfate Precipitation
Concentration: See vial for concentration
Source: Mice were immunized with a his-tagged recombinant full length p15 protein recognizing a 15kDa protein
References: 1) C. Sherr, et.al. (1995) Gene & Dev..9, 1149-11632) Sakellariou, S., et al. 'Immunohistochemical Expression of P15 (INK4B) and SMAD4 in Advanced Gastric Cancer.' Anticancer Research (2008), 28, 1079-1083
UniProt: P42772 (Human)
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
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