Mouse anti-Human Perforin, clone MRQ-23 (Monoclonal)

Clone Number: MRQ-23

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis, the cell death program. The expression of perforin is reportedly upregulated in activated CD8+ T-cells, natural killer cells and some CD4+ T-cells.

References: Chu PG, et al. Ann Diagn Pathol. 1999; 3:104-33/Bittmann I, et al. Arch. 2004; 445:375-81/d’Amore ES, et al. Pediatr Dev Pathol. 2007; 10:181-91

• SKU: SANMON3335
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON3335
• Green Labware: No
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG1
• Host: Mouse