Mouse anti-Keratin 18, clone RCK106, Purified (Monoclonal)

Clone Number: RCK106

Immunogen: Cytokeratins from the Human bladder carcinoma cell line T24

Concentration: 1 mg/ml

Storage buffer: PBS with 0.09% sodium azide

Additional info: Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in Human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 – 7.8. The individual Human Cytokeratins are numbered 1 to 20. The various epithelia in the Human body usually express Cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of matuRation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The Cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

References: Ramaekers et al. Exp Cell Res 1987;170:235-249/Raats et al. Cell Biol 1990;111:1971-1985/Smedts et al. Am J Pathol 1990;136:657-668

• SKU: SANMON3027
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON3027
• Green Labware: No
• Package Unit: 0,1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Western Blotting, Flow Cytometry, Immunocytochemistry
• Isotype: IgG1
• Host: Mouse