Clone Number: EBS-O-104
Immunogen: human PBL from a T-ALL patient
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: EBS-O-104 reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and also platelets but are absent on erythrocytes. MHC class I antigens play a role in class I MHCassociated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
References: Young NT et al. Hum Immunol 52(1): 1-11 (1997)/Krensky AM et al, Transplant Proc 28(6): 3026-8 (1996)/Hansen JA et al, Hematol Oncol Clin North Am 4(3): 507-515 (1990)