Clone Number: 2G7
Immunogen: VNTR 60mer glycosylated synthetic peptide BSA conjugate
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: VU-2G7 reacts with the protein core of MUC1, an apical cell side epithelial marker which is upregulated or switched on in the majority of carcinomas. The dominant epitope of VU2G7 includes the PDTR motif, located in the VNTR domain of MUC1. Binding of VU-2G7 is significantly enhanced when the threonine of the PDTR motif bears a GalNAc
References: Ryuko, K. et al. Tumor Biol. 21(4): 197-210 (2000)/Karsten, U. et al. Cancer. Res. 58(12): 2541-2549 (1998)