Clone Number: LO26
Immunogen: Prokaryotic recombinant fusion protein corresponding to the Myf-4 molecule.
Concentration: Greater than or equal to 13 mg/L
Storage buffer: Tissue culture supernatant with sodium azide
Additional info: Rhabdomyosarcomas are a class of myoblast-derived soft tissue sarcomas that usually express a number of muscle-specific genes and primarily affect children and young adults. Differentiation of myogenic cells is controlled by a set of regulatory genes including MyoD1, myogenin, Myf-5 and Myf-6. Myf-4 is the human homolog of myogenin. Its gene product, together with that of Myf-3, accumulates in the nucleus of differentiated cells.
References: Den Bakker MA et al. Histopathology. 2003; 43(3):297–299/Ingeholm P et al. APMIS. 2002; 110(9):639–645/Kumar S et al. Modern Pathology. 2000; 13(9):988–993