Mouse anti-Napsin A, clone MRQ-60

Clone Number: MRQ-60

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: Napsin is a pepsin-like aspartic proteinase in the A1 clan of the AA clade of proteinases. There are two closely related napsins, napsin A (NAPSA) and napsin B (NAPSB). Napsin A is involved in processing propeptide pulmonary surfactant protein B (proSP-B) in the lung. In normal tissue, Napsin A is expressed in type II pneumocytes of the lung and proximal tubules of the kidney. Napsin A is a useful marker for lung adenocarcinoma.

References: Jagirdar J. Arch Pathol Lab Med.; 132:384-96 (2008)/Bishop JA, et al.. Hum Pathol.; 41:20-5 (2010)/Ye J, et al. Appl Immunohistochem Mol Morphol.; 19:313-17 (2011)

• SKU: SANMON-RTU1273
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON-RTU1273
• Green Labware: No
• Package Unit: 7 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG1-k
• Host: Mouse