Clone Number: DO7
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: The antibody recognizes a 53 kDa phosphoprotein, identified as p53 suppressor gene product. It reactswith the mutant as well as wild type p53.1 Positive nuclear staining with this antibody has been shownto be a factor in breast carcinoma, lung carcinoma, colorectal carcinoma, urothelial carcinoma, andependymoma.2-8 Anti-p53 positivity has also been used to differentiate uterine serous carcinomafrom endometrioid carcinoma, as well as a marker for intratubular germ cell neoplasia.
References: Mauri FA et al. Int J Oncol 1999 Dec;15(6):1137-47/Caffo O et al. Clin Cancer Res 1996 Sep;2(9):1591-9/Bebenek M et al. Anticancer Res 1998 Jan-Feb;18(1B):619-23
English
Deutsch
