Mouse anti-Tenascin-C, clone EB2 (Monoclonal)

Clone Number: EB2

Immunogen: Purified tenascin-C from human fetal fibroblasts

Concentration: 100 ug/ ml

Storage buffer: PBS with 1% BSA & 0.1% sodium azide

Additional info: The antibody reacts with the 4th and 5th fibronectin-like repeats of human tenascin-C. It has been demonstrated that tenascin immunoreactivity in breast carcinoma cells could be indicative of metastasis and survival. Recent studies using retrospective material showed that the expression of tenascin in invasion border of early breast cancer significantly correlates with higher risk of distant metastasis. These studies have been continued now and the preliminary results clearly suggest that expression of tenascin in invasion border of early breast cancer is significantly associated with proliferative activity and higher risk of local recurrence. This result implicates a wide application for tenascin antibodies in the breast pathology.

References: Korhonen et al. J Histochem Cytochem 2000;48:1011-1020/Karjalainen et al. Am J Resp Crit Care Med 2000;161:2086-2091/Li et al. Rheumatol 2000;19:177-183

• SKU: SANMON7093
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON7093
• Green Labware: No
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human, Rabbit, Guinea Pig
• Clonality: Monoclonal
• Application: Immunohistochemistry (frozen), Western Blotting, ELISA
• Isotype: IgG1
• Host: Mouse