Application Note: Measured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-Leu-Arg-AMC. The IC₅₀ value is < 15 nM.
Form: Lyophilized powder
Buffer (with preservative): Batch dependent (please contact us for details)
Concentration:
Background: This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Uniprot ID: Q8BKV0
Region Sequence: C-terminal polyhistidine tag; Met1-Ile436 (NP_076178.1)
ExpressionSystem: Baculovirus-Insect Cells
Conjugation: Unconjugated
Full Name: sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3