Clone: MPO-1/1, 7.17.
Conjugate: FITC.
Immunogen: Purified human MPO.
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).
Recommended Usage: MPO, clone 7,17 is a mAb intended for identification of the myeloid lineage. MPO does not react with human lymph, thrombocytes and erythrocytes. It is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
Description: This antibody reacts with the intracellular enzyme, myeloperoxidase in peripheral blood granulocytes on cytospots in a characteristic granular pattern. Monocytes are negative or slightly positive while eosinophils and lymphocytes are negative. MPO antibodies stain promyelocytes, myelocytes, metamyelocytes and mature neutrophil granulocytes in bone marrow.
MPO is a tetrameric protein, each tetramer contains a two 60 kD heavy units and two 12 kD light units. It is a lysosomal hemoprotein stored in azurophilic granules.
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