Application Note: WB: 1:500-1:2000. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 540
Form: Liquid
Buffer (with preservative): PBS, 50% Glycerol, 0.02% sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016]
Uniprot ID: Q02817
Antigen Species: Human
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 4850-4950 of human MUC2 (NP_002448.4).
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: mucin 2, oligomeric mucus/gel-forming
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