Product Description: N3-Ph-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-Ph-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Applications: Cancer-programmed cell death
Formula: C11H8N4O4
CAS Number: 53053-08-0
Molecular Weight: 260.21
Compound Purity: 99.88
Research Area: Cancer
Solubility: DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)