Abbreviation: NF-kB p65
Target Synonym: NFKB3;p65;NF-kB p65;RELA;CMCU
Conjugation: Unconjugated
UNIProt ID: Q04206
Background: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human NF-kB p65/RelA
Dilution: WB 1:500-1:2000,IHC 1:50-1:100,IF 1:50-1:200