Application Note: WB: 1:500-1:2000. ICC/IF: 1:100-1:500. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 60
Form: Liquid
Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium Azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Uniprot ID: Q04206
Antigen Species: Human
Immunogen: A synthesized peptide derived from human RELA(Accession Q04206), corresponding to amino acid residues around phosphorylated Ser276.
Purification: Purified by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Conjugation: Unconjugated
Full Name: RELA proto-oncogene, NF-kB subunit
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