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Encompassing Amino Acids: 2-1036 (end)
Description: Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1, with K232A mutation, (Genbank Accession No. NM_004895), a.a. 2-1036(end) with N-terminal His-FLAG-tag, expressed in a baculovirus infected Sf9 cell expression system. MW = 120 kDa (calculated).
Format: Aqueous buffer solution
Formulation: 40mM Tris-HCl, pH 8.0, 110mM NaCl, 2.2mM KCl, 0.04% Tween-20, 100µg/ml FLAG peptide and 20% glycerol.
Genbank: NM_004895
Host Cell Line: Sf9 cells
Storage Stability: At least 6 months at -80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Tags: N-terminal His-FLAG-tag
Uniprot: Q96P20
Biosafety Level: Not applicable (BSL-1)
References: 1.Kummer, J.A., J. Histochem. Cytochem., 2007 May; 55(5):443-52.2.Manji, G.A., J. Biol. Chem. 2002 Mar 29; 277(13):11570-5.