NOX2/gp91phox Polyclonal Antibody, Rabbit

Abbreviation: NOX2/gp91phox

Target Synonym: AMCBX2;CGD;GP91-1;GP91-PHOX;GP91PHOX;IMD34;NOX2;p91-PHOX;CYBB

Conjugation: Unconjugated

UNIProt ID: P04839

Background: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human NOX2/gp91phox

Dilution: WB 1:500-1:2000

• SKU: ELSE-AB-93080-60
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-93080-60
• Green Labware: No
• Package Unit: 60 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit