Clone Name: C-10
Light Chain: Kappa
Application Note: IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 39
Positive Control: Seminoma
Specificity/Sensitivity: This antibody is recommended for detection of Oct-3A (Oct-4) and Oct-3B of mouse, rat and human.
Form: Liquid
Buffer (with preservative): Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]
Uniprot ID: Q01860
Antigen Species: Human
Immunogen: Amino acids 1-134 of OCT-4 of human origin
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: POU class 5 homeobox 1
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