OH-Glu-Val-Cit-PAB-MMAE, CAS 1895916-23-0

Product Description: OH-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (OH-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

Applications: Cancer-programmed cell death

Formula: C63H100N10O15

References: [1]Gemma E Mudd, et al. Discovery of BT8009: A Nectin-4 Targeting Bicycle Toxin Conjugate for the Treatment of Cancer. J Med Chem. 2022 Nov 10;65(21):14337-14347.

CAS Number: 1895916-23-0

Molecular Weight: 1237.53

Compound Purity: 99.92

Research Area: Cancer

Solubility: DMSO : 180 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-148245-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-148245-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK