Application Note: WB: 1-3μg/ml. IHC-P: 3.75μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 82
Positive Control: The peptide used to generate this antibody is available for purchase (GTX89992-PEP).
Specificity/Sensitivity: This antibody is expected to recognize both reported isoforms (NP_862820.1 and NP_036513.2).
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]
Uniprot ID: Q9UBD5
Antigen Species: Human
Immunogen: Peptide with sequence QKTDHVARLTWGGC, from the C Terminus of the protein sequence according to NP_862820.1; NP_036513.2.
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: origin recognition complex subunit 3
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