Abbreviation: Osteocalcin (BGLAP)
Target Synonym: BGLAP;BGP;OC;OCN;osteocalcin
Conjugation: Unconjugated
UNIProt ID: P02818
Background: This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human Osteocalcin
Dilution: WB 1:500-1:2000,IF 1:50-1:200